Additional File 1.

Alignment of IL-21 amino acid sequences. Squares above the alignment show predicted glycosylation sites from the opossum sequence. Residues Asp33 and Gln145 are important for receptor binding in humans and are denoted by a diamond [71]. Inverted triangles indicate cysteine residues that are conserved across species. Dots represent identity to Monodelphis domestica sequence. Sequences used for alignment: Homo sapiens (Q9HBE4), Mus musculus (NP_068554.1), Gallus gallus (NP_001020006.1), Canis familiaris (NP_001003347.1), Sus scofa (Q76LU6), Bos taurus (Q76LU5).

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Wong et al. Immunome Research 2006 2:4   doi:10.1186/1745-7580-2-4