|
The table lists AROC performance of protectivity classifications for individual proteins based on different parameters |
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| AROC |
antigenicity |
modification |
variability |
combined |
|
|
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| proteins where AROC < = 0.35 |
10 |
7 |
16 |
7 |
| proteins where AROC > = 0.65 |
21 |
19 |
16 |
30 |
| AROC median non-contaminated |
0.62 |
0.56 |
0.56 |
0.65 |
| AROC median contaminated |
0.55 |
0.59 |
0.45 |
0.63 |
|
Note that measured by the AROC median non-contaminated proteins unexpectedly seem to perform better than contaminated sequences. The combined classifier yields higher median AROC values than classifications based on individual parameters. Possibly more important, the number of proteins with AROC values > = 0.65 is substantially higher when comparing the combined score (protein count 30) with the best single score antigenicity (protein count 21). | ||||
Sollner et al. Immunome Research 2008 4:1 doi:10.1186/1745-7580-4-1 |
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