Expression analysis of G Protein-Coupled Receptors in mouse macrophages

doi:10.1186/1745-7580-4-5

Immunome Research

Volume 4

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Lattin JE
Schroder K
Su AI
Walker JR
Zhang J
Wiltshire T
Saijo K
Glass CK
Hume DA
Kellie S
Sweet MJ

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Schroder K
Su AI
Walker JR
Zhang J
Wiltshire T
Saijo K
Glass CK
Hume DA
Kellie S
Sweet MJ
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Expression analysis of G Protein-Coupled Receptors in mouse macrophages

Jane E Lattin¹ , Kate Schroder¹ , Andrew I Su² , John R Walker² , Jie Zhang² , Tim Wiltshire² , Kaoru Saijo³ , Christopher K Glass³ , David A Hume⁴ , Stuart Kellie¹^,5 and Matthew J Sweet¹^,5

¹Cooperative Research Centre for Chronic Inflammatory Diseases and Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, 4072, Australia

²The Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA

³The Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651, USA

⁴The Roslin Institute, University of Edinburgh, Roslin EH25 9PS, Scotland, UK

⁵School of Molecular and Microbial Sciences, University of Queensland, Brisbane, Queensland, 4072, Australia

author email corresponding author email

Immunome Research 2008, 4:5doi:10.1186/1745-7580-4-5


Published:	29 April 2008

Additional files

Additional file 1:

GPCR expression in Mouse Macrophages. The table lists all GPCRs expressed in mouse macrophages.

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Additional file 2:

Macrophage-restricted GPCRs. The data provided demonstrates the macrophage-restricted expression of P2ry12, Edg5 and Gpr18 mRNA. Micro-array analysis of P2ry12 (A), Edg5 (B) and Gpr18 (C) mRNA expression across a panel of 91 murine cell types and tissues. Data points show normalised values and similar cell types are grouped according to bar colour; blue indicates primary macrophage cell types, purple indicates bone-related cell types, red indicates other immune cell types, green indicates stem cell populations, orange indicates whole tissue samples, yellow indicates neuronal and retinal cell types and pink indicates cell lines. Additional file 3 gives details of the 91 cell types and tissues profiled.

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Additional file 3:

Cell panel sample types (legend key for figure 1 and 2 and additional file 1). The table provides a full list of the cell lines and tissues profiled in the micro-array analysis.

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