Table 3

Major cancer vaccine technologies.

Vaccine antigen status

Vaccine technology


Defined antigen

Dendritic cell (peptide)

Dendritic cell (protein)

Dendritic cell (specific RNA)

Dendritic cell (virus)

Viral vector (antigen)

Viral vector (other)

Naked DNA

Protein

Peptides

Anti-idiotype

Antigen-specific adjuvant

Other


Undefined antigen

Dendritic cells (tumor cell pulsed)

Dendritic cells (lysate pulsed)

Dendritic cells (allo-lysate pulsed)

Allogeneic Dendritic cells (lysate pulsed)

Dendritic cells (antigen)

Dendritic cells (non-specific DNA)

Dendritic cells (non-specific RNA)

Dendritic cells (idiotype)

Oncolytic virus

Autologous (tumor lysate)

Allogeneic (tumor lysate)

Autologous (tumor cell)

Allogeneic (tumor cell)

Autologous (T cell)

Autologous (lymphocytes)

Autologous (PBMC)

Immunomodulators

Immune activators

Other non-cancer vaccines

Other


More details about technological platforms for cancer vaccines can be found in [20].

Cao et al. Immunome Research 2008 4:7   doi:10.1186/1745-7580-4-7

Open Data