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Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?

Maya F Kotturi, Erika Assarsson, Bjoern Peters, Howard Grey, Carla Oseroff, Valerie Pasquetto and Alessandro Sette*

Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA

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Immunome Research 2009, 5:3 doi:10.1186/1745-7580-5-3

Published: 17 June 2009

Additional files

Additional file 1:

Recognition of additional A2.1-restricted VACV T cell epitopes by human A2-positive VACV vaccinees. The data provided represent the net SFC/106 PBMCs of the human A2-positive VACV vaccinees in response to epitopes originally identified in A2.1 Tg mice.

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